South Dakota State and Iowa face off for a college football Week 1 matchup on FS1 Saturday at noon.

The South Dakota State Jackrabbits are coming off a stellar 11-2 regular season. Their final game of 2021 ended in defeat as they lost their FCS semifinal game to Montana State. Similarly, the Hawkeyes lost their last matchup of 2021 when they fell 20-17 to Kentucky in the Citrus Bowl. Iowa did finish the regular season with a 10-3 overall record.

Both squads began last year with season-opening wins. So who gets the edge this year in Week 1?

Here’s everything you need from a betting perspective on the game between South Dakota State and Iowa from the point spread, moneyline and total over/under (odds via FOX Bet).

South Dakota State @ Iowa (12 p.m. ET Saturday, FS1)

Point spread: Iowa -18 (Iowa favored to win by more than 18 points, otherwise South Dakota State covers)
Moneyline: Iowa -714 favorite to win (bet $10 to win $11.40 total); South Dakota State +450 underdog to win (bet $10 to win $55 total)
Total scoring over/under: 44 points scored by both teams combined

The Hawkeyes were 7-6-1 against the spread (ATS) per FOX Sports Research last season. And the under hit in eight of those 14 games. Iowa is 2-6 ATS and 7-1 straight up (SU) when facing non-FBS opponents since 2010. 

Fun fact: The Hawkeyes lost to North Dakota State in 2016 as 14-point favorites.

South Dakota State is 7-2 ATS and 2-7 SU playing FBS opponents since 2010. The Jackrabbits defeated Kansas in 2015 as 2-point favorites and took down Colorado State as 2-point underdogs last season.

So are you wagering on the underdog Jackrabbits to hop away with the upset? Or is your money on the Hawkeyes in Week 1? Head over to FOX Bet to get in on the action now!

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